Patent Sequence Listing Services

Our Features and Strengths:

  • Experts familiar with PTO Compliance: Team of experts familiar with WIPO, USA and other jurisdictional standards and hold advanced degrees in Biotechnology and Life Sciences.
  • Understanding: TSLC consults with the client and furnishes any additional details required for preparing the sequence listing as required by PTO.
  • At TSLC it is an everyday procedure to produce standardized sequence listings using PatentIn 3.5 and BiSSAP software and additionally using other in-house algorithms to optimize efforts and produce custom-based results.
  • Preparing error-free PTO Compliant Listings: With the team of experts, TSLC has produced over 50+ error-free sequence listings in PTO acceptable format, helping patent drafters.
  • Pricing and Turn-Around: Offering budget-friendly cost models with quick turn-around time.

Unique Pricing Model:

  • Per Sequence cost – $1.5 per sequence (However, bare minimum of USD 99 would be there, covering till 60 sequences in an application. After that, every additional sequence shall cost $1.5/sequence.)

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About Sequence Listing Services:

Biotechnology involves the exploitation of biological processes for industrial and other related purposes. This branch of study is a combination of science and technology and contributes to the advancement in the field of life sciences for creating genetic modifications of living organisms.

A large portion of inventions and advancements (antibodies, GMOs, biomarkers) in biotechnology involve sequencing genes, amino acid and nucleotide bases to transform the genetic make-up to produce modified (enhanced) living organisms. 

A gene consists of a chain of polynucleotides consisting of the nucleotide sequences composed of bases – Adenine (A), Thymine (T), Guanine (G) and Cytosine (C) that code for amino acids. These amino acids are the building blocks of proteins and there are 20 naturally occurring amino acids. A special one-letter or triple letter codes represent each amino acid.

The sequence listings thus identify the gene or the protein by a “Sequence ID No.”. One Sequence ID Number (SEQ ID No.) corresponds to a single gene/ protein and the complete sequence listing provides the list of entire sequence.

Why Sequence Listing:

  • There are inventions dealing with peptide and/or DNA sequences such as inventions related to biomarkers, Antibodies, Oligonucleotides etc. where there is a requirement to file the DNA/Peptide sequences at the time of filing the patent application.
  • The sequences provided in the patents are to comply with the PTO filing regulations following the required norms and regulations.
  • Patent offices require applicants to file sequence listings in a standardized format (US 37 C.F.R. §§ 1.821-1.825 and WIPO standard ST. 25) for any DNA Sequence consisting of ten (10) or more nucleotides and/or any amino acid Sequence consisting of four (4) or more defined amino acids.

Advantages of Sequence Listings:

  • Within a patent document, genetic sequences are viewed both legally and practically as either chemical compounds or as information-encoding elements. Their structure and function holds great importance within the context of patent eligibility or infringement issues.
  • Sequence listing allows the applicant to create a single listing that is acceptable to all receiving Offices, Preliminary Examining Authorities and International Searching Authorities for international phase purposes, as well as to all designated and elected National Phase Offices.

Salient Features:

  • Sequence listings prepared with strict compliance to US 37 C.F.R. §§ 1.821-1.825 and WIPO standard ST. 25.
  • PatentIn Version 3.5 software (see MPEP § 2430) generates sequence listings that meet all of the requirements of WIPO Standard ST.25

The biological sequences are prepared for all the following methods of submission:

  • Disc (containing an ASCII text computer-readable form on Disk/CD).
  • “Paperless Submission” (submissions of CD, without paper)
  • ASCII text (uploaded via Electronic Filing System (EFS)

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Case Studies:

Case Study I

One of our client of an US based law firm wanted to file an International Patent Application; wherein the patent application comprised nucleotide and protein sequences. Hence, to meet US (37 CFR §§1.821-1.825) and foreign (WIPO Standard ST.25) Sequence Listing requirements, the client was interested in preparing a computer readable “Sequence Listing” document required at the time of filing of the patent application containing biological sequences.

In the sequence listing project, TSLC prepared an ASCII text computer-readable “Sequence Listing” document using PatentIn software 3.5 version.The DNA/RNA sequences also included modified nucleotides which were mentioned in the comment section for Artificial sequences/Unknown organism.

Case Study II

In another case, a client approached TSLC to get corrections done in sequence listing for which objections have been received from the USPTO. The client was unaware of all the errors in the report. So, he wanted us to help him with identifying and consequently correcting all the errors in the report.

After understanding the client requirements, our experts prepared a corrected version for the sequence listing document which was aligned with US (37 CFR §§1.821-1.825) and acceptable by the USPTO.

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